There is limited clinical experience with lemborexant overdose. In clinical pharmacology studies, healthy patients who were administered multiple doses of up to 75 mg (7.5 times the maximum recommended dose) of lemborexant showed dose-dependent increases in the frequency of somnolence. There is no available specific antidote to an overdose of lemborexant. In the event of overdose, standard medical practice for the management of any overdose should be used. A certified poison control center should be contacted for updated information.