Contraindications

[lmidafenacin (UritosĀ®) is contraindicated in the following patients]

  1. Patients with urinary retention [Symptoms may be aggravated due to inhibition of bladder contraction during urination caused by the anticholinergic effect of this product.]

 

  1. Patients with occluded pyloric region/duodenum/intestine or paralytic ileus [Symptoms may be aggravated due to inhibition of contraction and motility of gastrointestinal smooth muscles caused by the anticholinergic effect of this product.]

 

  1. Patients with decreased gastrointestinal motility [Symptoms may be aggravated due to inhibition of contraction and motility of gastrointestinal smooth muscles caused by the anticholinergic effect of this product.]

 

  1. Patients with angle closure glaucoma [Symptoms may be aggravated due to an increase in intraocular pressure caused by the anticholinergic effect of this product.]

 

  1. Patients with myasthenia gravis [Symptoms may be aggravated due to a decrease in muscle tone caused by the anticholinergic effect of this product.]

 

  1. Patients with severe heart disease [Symptoms may be aggravated since abnormal electrocardiographic findings including extrasystoles have been reported.]

 

  1. Patients with a history of hypersensitivity to any of the components of this product.