Dosage & Administration

Donepezil hydrochloride (ARICEPT®) 23 mg tablets can be taken once daily in the evening just prior to retiring and can be taken with or without food or as prescribed by the physician. Donepezil hydrochloride (ARICEPT®) 23 mg tablets should not be split or crushed and should be swallowed whole with water.

The recommended starting dose of donepezil hydrochloride is 5 mg once daily. A dose of 10 mg

should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.

Patients who have been established on 10 mg of donepezil hydrochloride daily for at least 3 months can be administered one Donepezil hydrochloride (ARICEPT®) 23 mg tablets once daily.


This information is exclusively for healthcare professionals. The contents of this page are for information only and not a substitute for professional medical advice.

Are you a healthcare professional?